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Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal
Authors:Komáromi Anna  Novák Zoltán
Affiliation:Department of Organic Chemistry, Institute of Chemistry, E?tv?s Loránd University, Pázmány Péter stny. 1/a, Budapest, Hungary.
Abstract:Palladium on charcoal serves as an efficient and reusable solid supported catalyst for the Sonogashira coupling of aryl chlorides with terminal acetylenes in the presence of a bulky, electron-rich biphenyl type ligand (XPhos), without copper co-catalyst.
Keywords:
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