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Pseudouridines in rRNA helix 69 play a role in loop stacking interactions |
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| Authors: | Desaulniers Jean-Paul Chang Yu-Cheng Aduri Raviprasad Abeysirigunawardena Sanjaya C SantaLucia John Chow Christine S |
| Affiliation: | Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA. |
| Abstract: | The (1)H NMR spectra of RNAs representing E. coli 23S rRNA helix 69 with [1,3-(15)N]pseudouridine modification at specific sites reveal unique roles for pseudouridine in stabilizing base-stacking interactions in the hairpin loop region. |
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