|
|||||
|
|
Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer |
|
| Authors: | Yu Li Hui Bin Zhang Wen Long Huang Xia Zhen Yun Man Li |
| Affiliation: | Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, China |
| Abstract: | Tetrahydroisoquinoline derivatives were synthesized and their multidrug resistance reversal activities were evaluated in vitro.The results showed that some of the synthetic compounds had higher multidrug resistance (MDR)reversal activities than verapamil. |
| Keywords: | Tetrahydroisoquinoline derivatives Synthesis Multidrug resistance (MDR) Peptoids |
| 本文献已被 CNKI 维普 万方数据 ScienceDirect 等数据库收录！ | |
| 点击此处可从《中国化学快报》浏览原始摘要信息 | |
| 点击此处可从《中国化学快报》下载全文 | |