One-pot allyl-/crotylboration-Prins cyclization of aldehydes |
| |
| Authors: | P. Veeraraghavan Ramachandran Pravin D. Gagare |
| |
| Affiliation: | Herbert C. Brown Center for Borane Research, Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA |
| |
| Abstract: | Multi-substituted tetrahydropyrans (THPs) have been prepared via a one-pot, In(OTf)3-catalyzed, sequential allyl-/crotylboration-Prins cyclization. The homoallylic borate intermediate formed during the allyl- and crotylboration was converted in situ to an oxocarbenium ion and trapped with a nucleophile. The reaction has been extended to include a one-pot allylboration-cross Prins cyclization as well. |
| |
| Keywords: | Prins cyclization Allylboration Crotylboration Oxocarbenium ion Tetrahydropyran |
| 本文献已被 ScienceDirect 等数据库收录！ |
