Atom arrangement strategy for designing a turn-on 1H magnetic resonance probe: a dual activatable probe for multimodal detection of hypochlorite |
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| Authors: | Doura Tomohiro Nonaka Hiroshi Sando Shinsuke |
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| Affiliation: | INAMORI Frontier Research Center, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan. |
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| Abstract: | The first dual activatable hypochlorite ((-)OCl)-sensing probe was developed, based on a new proof-of-concept design involving signal-activatable (1)H chemical probes using the triple-resonance NMR technique. The probe enabled fluorescence-(1)H MR dual turn-on detection of (-)OCl in solution and in crude tissue extracts. |
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