| 粘液素对草酸钙晶体生长的影响 |
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| 引用本文： | 陈德志,欧阳健明.粘液素对草酸钙晶体生长的影响[J].化学研究与应用,2005,17(1):61-63. |
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| 作者姓名： | 陈德志 欧阳健明 |
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| 作者单位： | 暨南大学生物矿化与结石病防治研究所,广东,广州,510632;暨南大学生物矿化与结石病防治研究所,广东,广州,510632 |
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| 基金项目： | 广东省重点攻关项目(C31401)，国家自然科学基金重点项目(20031010)，广东省自然科学基金重点项目(013202)，广东省“千百十工程”优秀人才培养基金 (Q0 2 0 60 ) |
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| 摘 要： | 泌尿系结石是一种常见疾病。在70％以上的结石中，草酸钙(CaOxa)单独或和其它钙盐共同为主要成分。一般认为正常人不形成尿石是其尿液中存在的抑制剂抑制了CaOxa晶体的成核、生长、聚集或固相转化。
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| 关 键 词： | 草酸钙 粘液素 尿结石 |
| 文章编号： | 1004-1656(2005)01-0061-03 |
| 修稿时间： | 2004年1月5日 |
Investigation on growth of calcium oxalate crystal in the presence of mucin |
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| CHEN De-zhi,OUYANG Jian-ming.Investigation on growth of calcium oxalate crystal in the presence of mucin[J].Chemical Research and Application,2005,17(1):61-63. |
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| Authors: | CHEN De-zhi OUYANG Jian-ming |
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| Institution: | CHEN De-zhi,OUYANG Jian-ming~* |
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| Abstract: | The influence of mucin on the growth of calcium oxalate crystals was investigated by means of scanning electron microscopy and X-ray diffraction. In the control systems without mucin, calcium oxalate monhydrate(COM) crystals were the polymorphs without uniforn shape, and the (010) crystal face of COM was preferential grown.However,in the presence of mucin both the size and number of COM crystals were decreased, and the intensity of the diffraction peak of (101) face was strengthened in the debt of (010) face of COM crystals. It indicated that mucin can inhibit both the nucleation and growth of COM crystals, so mucin can prevent the formation of CaOxa stones. |
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| Keywords: | calcium oxalate mucin urinary stone |
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