A general and efficient FeCl3-catalyzed nucleophilic substitution of propargylic alcohols |
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| Authors: | Zhan Zhuang-ping Yu Jing-liang Liu Hui-juan Cui Yuan-yuan Yang Rui-feng Yang Wen-zhen Li Jun-ping |
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| Affiliation: | Department of Chemistry and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. zpzhan@xmu.edu.cn |
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| Abstract: | A general and efficient FeCl3-catalyzed substitution reaction of propargylic alcohols with carbon- and heteroatom-centered nucleophiles such as allyl trimethylsilane, alcohols, aromatic compounds, thiols, and amides, leading to the construction of C-C, C-O, C-S and C-N bonds, has been developed. |
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