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A constructive synthetic approach for reduction of nitro heterocyclics- characterization and degradation studies
Affiliation:1. Department of Chemistry, Raghu Engineering College, Visakhapatnam, 531162, Andhra Pradesh, India;2. Department of Chemistry, Krishna University, Andhra Pradesh, 521004, India;1. Selvamm Arts and Science College, Namakkal, 637 003, Tamilnadu, India;2. Adiyamaan College of Engineering, Hosur, 635 209, Tamilnadu, India;3. Department of Physics, Periyar University, Salem, 636 011, Tamilnadu, India;1. Graduate School of Environmental Engineering, The University of Kitakyushu, 1-1 Hibikino, Wakamatsu, Kitakyushu, Fukuoka, 808 0135, Japan;2. Department of Creative Engineering, National Institute of Technology, Ariake College, 150 Higashihagio, Omuta, Fukuoka, 836-8585, Japan;1. Department of Physics, Andhra University, Visakhapatnam, A.P, India;2. Department of Basic Science and Humanities, Raghu Institute of Technology (A), Dakamarri, Bheemunipatnam Mandal, Visakhapatnam, A.P., India;3. Department of Physics, Sri Venkateswara College, Benito Juarez Marg, Dhaula, University of Delhi, New Delhi, 110021, India;4. Department of Engineering Physics, AUCE (A), Andhra University, Visakhapatnam, A.P, India;5. Department of Physics, College of Natural and Computational Science, Wolkite University, Wolkite, Ethiopia;1. University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, 160 014, India;2. Department of Chemistry and Centre of Advanced Studies, Panjab University, Chandigarh, 160 014, India;3. Vaxine Pty Ltd, Warradale, Australia;4. College of Medicine and Public Health, Flinders University, Adelaide, Australia;5. National Interdisciplinary Centre of Vaccine, Immunotherapeutics and Antimicrobials, Panjab University, Chandigarh, 160 014, India;1. GIET University, Gunupur, Odisha, India;2. International PranaGraf Mintech Research Centre (IGMRC), Odisha, India;3. Centurion University of Technology and Management, Odisha, India;1. Department of Physics, Science Faculty, Eskişehir Technical University, Eskişehir, Turkey;2. Department of Physics, Science Faculty, Ondokuz Mayıs University, Samsun, Turkey;3. Department of Physics, Science Faculty, Ege University, Izmir, 35040, Turkey
Abstract:A novel synthetic approach was proposed for a metal free reduction of nitro aromatic compounds to the resultant amines by sodium dithionite. A series of nitro compounds containing various reducible functional groups were chemoselectively reduced in good to excellent yield. Instantaneously some of the products are chemically degraded and all are characterized by spectral methods.
Keywords:Heterocyclic  Sodium dithionite  Degradation  Spectral methods
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