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A 3D QSAR CoMFA study of non-peptide angiotensin II receptor antagonists
Authors:Laura Belvisi  Gianpaolo Bravi  Giovanna Catalano  Massimo Mabilia  Aldo Salimbeni  Carlo Scolastico
Affiliation:(1) Organic and Industrial Chemistry Department, C.N.R. (National Research Council) Centre for the Study of Organic and Natural Compounds, University of Milan, Via Venezian 21, I-20133 Milan, Italy;(2) S.IN-Soluzioni Informatiche s.a.s., Via Salvemini 9, I-36100 Vicenza, Italy;(3) Medicinal Chemistry Department, Institute LusoFarmaco d'Italia S.p.a., Via Carnia 26, I-20132 Milan, Italy
Abstract:
Keywords:Renin-angiotensin system  Binding requirements  Steric and electrostatic interaction energy  PLS
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