Chemoselective construction of substituted conjugated dienes using an olefin cross-metathesis protocol |
| |
| Authors: | Funk Timothy W Efskind Jon Grubbs Robert H |
| |
| Institution: | Arnold and Mabel Beckman Laboratory of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA. |
| |
| Abstract: | Reaction: see text] Various substituted conjugated dienes have been made by olefin cross-metathesis. Using either electronic or steric "protection," one of the olefins of the conjugated diene was deactivated relative to the other for cross-metathesis. The reactions proceed with very high chemoselectivity and, when steric deactivation is used, very high diastereoselectivity. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
