一种Fe3+荧光探针的合成及其检测性能研究

金属离子的高效检测对于人类健康和环境保护极其重要。本文通过对甲基苯磺酸催化下3-脱氢莽草酸甲酯与若丹明6G乙二胺缩合的芳构化反应合成了一种检测Fe~(3+)的荧光探针分子Rh M606。该探针分子在乙醇溶液中特异性地与Fe~(3+)络合,导致若丹明内酰胺开环,在553nm处出现强的荧光发射峰。该荧光探针对Fe~(3+)具有良好的选择性,可定量检测水中的Fe~(3+),检测限为3. 93μmol/L。

Synthesis and Properties of a Fluorescence Probe for the Detection of Fe3+ ions

The detection of metal ions is extremely important for human health and environmental protection. In this work, a fluorescent probe for the detection of Fe3+ ions was synthesized based on aromatization reaction of methyl 3-dehydroshikimate (3-MDHS). The target probe RhM606 was synthesized by condensation reaction between rhodamine-6G ethylenediamine and 3-MDHS, which was catalyzed by p-tolueneSsulfonicSacid. The probe molecules have a specific coordination effect with Fe3+ ions in ethanol solution, which induce the opening of the lactam ring and generate a strong fluorescence emission at 553 nm. The fluorescent probe has a good selectivity and can quantitatively determinate Fe3+ ions in aqueous solution. The limit of detection is 3.93 uM.