A new classification system for bacterial Rieske non-heme iron aromatic ring-hydroxylating oxygenases |
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| Authors: | Ohgew Kweon Seong-Jae Kim Songjoon Baek Jong-Chan Chae Michael D Adjei Dong-Heon Baek Young-Chang Kim Carl E Cerniglia |
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| Affiliation: | (1) Microbiology Division, National Center for Toxicological Research/U.S. FDA, Jefferson, AR 72079, USA;(2) Division of Personalized Nutrition & Medicine, National Center for Toxicological Research/U.S. FDA, Jefferson, AR 72079, USA;(3) Biotechnology Center for Agriculture and the Environment, Cook College, Rutgers University, New Brunswick, NJ 08901, USA;(4) Department of Health Norfolk Department of Public Health Bureau of Laboratories, , Norfolk, VA 23510, USA;(5) Department of Oral Microbiology and Immunology, School of Dentistry, Dankook University, Chonan, 330-714, Republic of Korea;(6) School of Life Science, Chungbuk National University, Cheongju, Chungbuk, 361-763, Republic of Korea |
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| Abstract: | Background Rieske non-heme iron aromatic ring-hydroxylating oxygenases (RHOs) are multi-component enzyme systems that are remarkably diverse in bacteria isolated from diverse habitats. Since the first classification in 1990, there has been a need to devise a new classification scheme for these enzymes because many RHOs have been discovered, which do not belong to any group in the previous classification. Here, we present a scheme for classification of RHOs reflecting new sequence information and interactions between RHO enzyme components. |
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