4-Hydroxy-2-quinolones 142. 4-Methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid anilides as potential diuretics |
| |
| Authors: | I V Ukrainets N L Bereznyakova V A Parshikov O I Naboka |
| |
| Institution: | (1) National University of Pharmacy, Kharkiv, 61002, Ukraine |
| |
| Abstract: | A large series of 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid anilides has been prepared as potential diuretic agents.
The effect of all of the synthesized compounds on the urinary function of the kidney has been investigated. The appearance
of a “structure — diuretic activity” relationship is discussed.
__________
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 239–245, February, 2008. |
| |
| Keywords: | anilides diuretics 4-methyl-2-oxo-1 2-dihydroquinoline-3-carboxylic acid amidation |
| 本文献已被 SpringerLink 等数据库收录！ |
|
