| 铈铽共惨杂氟化镧纳米晶体的快速合成和荧光特性 |
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| 引用本文： | 陈良冬,郑小睿,丁 耘,喻学锋,李 雁.铈铽共惨杂氟化镧纳米晶体的快速合成和荧光特性[J].无机化学学报,2009,25(2):285-289. |
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| 作者姓名： | 陈良冬 郑小睿 丁 耘 喻学锋 李 雁 |
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| 作者单位： | 1. 武汉大学中南医院肿瘤科,肿瘤生物学行为湖北省重点实验室,武汉,430071
2. 武汉大学物理科学与技术学院,武汉,430072 |
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| 摘 要： | 用一种简单的方法快速合成了水溶性铈铽共惨杂氟化镧纳米晶体。这种荧光纳米晶体直径只有14 nm，具有很好的生物相容性，并且在活体干细胞中显示出很强的荧光。结果表明这种铈铽共惨杂氟化镧纳米晶体可作为一种有效的生物荧光标记材料。
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| 关 键 词： | 生物标记 稀土元素 纳米晶体 荧光 |
Rapid Synthesis of Biocompatible LaF3:Ce,Tb Nanocrystals with Bright Fluorescence |
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| CHEN Liang-Dong,ZHENG Xiao-Rui,DING Yun,YU Xue-Feng and LI Yan.Rapid Synthesis of Biocompatible LaF3:Ce,Tb Nanocrystals with Bright Fluorescence[J].Chinese Journal of Inorganic Chemistry,2009,25(2):285-289. |
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| Authors: | CHEN Liang-Dong ZHENG Xiao-Rui DING Yun YU Xue-Feng and LI Yan |
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| Institution: | Department of Oncology, Zhongnan Hospital of Wuhan University & Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, 430071,Department of Physics, Wuhan University, Wuhan 430072,Department of Physics, Wuhan University, Wuhan 430072,Department of Physics, Wuhan University, Wuhan 430072 and Department of Oncology, Zhongnan Hospital of Wuhan University & Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, 430071 |
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| Abstract: | Water-soluble fluorescent LaF3:Ce,Tb nanocrystals were synthesized rapidly by using a simple route in aqueous solution at 75℃. The water-soluble, small nanocrystals with an average diameter of 14 nm were demonstrated to be biocompatible and exhibited bright fluorescence in living hepatocellular carcinoma cell line HCCLM6 cells. The results indicate that the LaF3:Ce,Tb nanocrystals have the potential to be used as an alternative biological fluorescence probe. |
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| Keywords: | biolabels rare-earth nanocrystals fluorescence |
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