Niobium(V) chloride‐catalyzed synthesis of α‐aminonitriles with simultaneous reaction of aldehydes,amines and trimethylsilyl cyanide |
| |
| Authors: | Anjoy Majhi Sung Soo Kim Ho Sub Kim |
| |
| Institution: | Department of Chemistry, Inha University, Incheon 402‐751, South Korea |
| |
| Abstract: | A simple and efficient one‐pot method has been developed for the synthesis of α‐aminonitriles by concurrent reaction of aldehydes, amines and trimethylsilyl cyanide with a catalytic amount of NbCl5 (10 mol%) in CH3CN at room temperature. Copyright © 2008 John Wiley & Sons, Ltd. |
| |
| Keywords: | NbCl5 catalysis aldehydes amines trimethylsilyl cyanide α ‐aminonitriles |
|
|
