Constituents from the stems of Hibiscus taiwanensis |
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| Authors: | Wu Pei-Lin Wu Tian-Shung He Cai-Xia Su Chia-Hao Lee Kuo-Hsiung |
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| Affiliation: | Department of Chemistry, National Cheng Kung University, Taiwan. wupl@mail.ncku.edu.tw |
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| Abstract: | Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9'-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma. |
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