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Determination of the stability of omeprazole by means of differential scanning calorimetry
Authors:M. A. Ruiz  I. Reyes  A. Parera  V. Gallardo
Affiliation:(1) Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Granada, 18071 Granada, Spain
Abstract:Differential scanning calorimetry was used to study the stability of omeprazole in two forms: granules and powder. The drug was subjected to light, elevated temperature (40 and 60°C) and different pH values. The greatest alterations in stability were caused by pH, followed by light.
Keywords:differential scanning calorimetry  omeprazole  pH  stability
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