Synthesis of multifunctional Fe3O4 core/hydroxyapatite shell nanocomposites by biomineralization |
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| Authors: | Huang Chi Zhou Yangbo Tang Zhaomin Guo Xing Qian Zhiyong Zhou Shaobing |
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| Institution: | School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, P. R. China. |
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| Abstract: | Superparamagnetic nanoparticles with surface functional groups (-OH, -COOH and -NH(2)) were modified by in situ deposition of hydroxyapatite (HA) on the materials' surface through the biomineralization process to form Fe(3)O(4) core/hydroxyapatite shell nanocomposites. They possess potential applications as targeted carriers for antitumor drugs and as bone tissue engineering scaffolds by integrating multiple functions into a single nanosystem. |
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