| One-pot synthesis of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives via the three-component reaction of 1,2-diamines,ethyl pyruvate and α-bromo ketones |
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| 作者姓名： | Mohammad Piltan |
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| 作者单位： | Department of Chemistry, Sanandaj Branch, Islamic Azad University, P.O. Box 618, Sanandaj, Iran |
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| 基金项目： | Sanandaj Branch,Islamic Azad UniversityResearch Council for the financial support of this research |
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| 摘 要： | A simple synthetic protocol has been developed involving the three-component reaction between 1,2-diamines, ethyl pyruvate and a-bromo ketones in the presence of Fe Cl3 as a catalyst. A number of pyrrolo1,2-a]quinoxaline and pyrrolo1,2-a]pyrazine derivatives were synthesized in excellent yields using this protocol.
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| 关 键 词： | 丙酮酸乙酯 吡嗪衍生物 一锅合成 吡咯 二胺 反应 溴代 成分 |
| 收稿时间： | 19 February 2014 |
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