| Synthesis of tetrahydro-β-carbolines from phthalic anhydrides and tryptamine |
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| 作者姓名： | Yan-Ni Sun Cui-Ling Wang Ning Zhang Zheng Wang Zhu-Lan Liu Jian-Li Liu |
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| 作者单位： | Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China |
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| 基金项目： | the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT1174);the National Natural Science Foundation of China(Nos.20872118,30070905);the Key Lab Fund of Shaanxi Province of China(Nos.2010JS097,11JS090,12JS110);the Foundation of the Education Department of Shaanxi Province(No.12JK1010) |
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| 摘 要： | Tetrahydro-b-carbolines with strictosamide skeleton have been synthesized via intermolecular condensation, selective reduction, and intramolecular cyclization starting from phthalic anhydrides and tryptamine. The reactions are carried out under mild conditions with a wide range of substrates and functional groups.
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| 关 键 词： | Phthalic anhydride Tryptamine Tetrahydro-&beta -carboline Strictosamide |
| 收稿时间： | 3 April 2014 |
Synthesis of tetrahydro-β-carbolines from phthalic anhydrides and tryptamine |
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| Yan-Ni Sun,Cui-Ling Wang,Ning Zhang,Zheng Wang,Zhu-Lan Liu,Jian-Li Liu.Synthesis of tetrahydro-β-carbolines from phthalic anhydrides and tryptamine[J].Chinese Chemical Letters,2014,25(11):1503-1506. |
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| Authors: | Yan-Ni Sun Cui-Ling Wang Ning Zhang Zheng Wang Zhu-Lan Liu Jian-Li Liu |
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| Institution: | Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China |
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| Abstract: | Tetrahydro-b-carbolines with strictosamide skeleton have been synthesized via intermolecular condensation, selective reduction, and intramolecular cyclization starting from phthalic anhydrides and tryptamine. The reactions are carried out under mild conditions with a wide range of substrates and functional groups. |
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| Keywords: | Phthalic anhydride Tryptamine Tetrahydro-b-carboline Strictosamide |
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