水中药物和个人护理品分析方法研究进展

随着社会经济发展水平的提高和医疗条件的改善,药物和个人护理品(PPCPs)的使用种类及总量均显著增加,造成环境中PPCPs的残留浓度不断升高,进而会对水环境生态安全及人类和动植物的健康造成潜在危害和严重威胁.由于开发建立快速、灵敏、高效的PPCPs定性、定量分析方法是探究其存在、去除及毒性的前提,因此本文对水中PPCP...

Research Progress in Determination Methods of Pharmaceutical and Personal Care Products in Water

As raising of the level of socio-economic development and improving of medical conditions, the use ofpharmaceutical and personal care products (PPCPs) has increased significantly in both type and total volume,resulting in increasing residual concentrations of PPCPs in the environment, which in turn can pose a potential hazardand serious threat to the ecological safety of the aquatic environment and the health of humans, animals and plants.Since the development of rapid, sensitive and efficient qualitative and quantitative analytical methods for PPCPs is aprerequisite for investigating their presence, removal and toxicity, this paper summarizes the principles, advantagesand disadvantages of the analytical methods (pretreatment and detection methods) for PPCPs in water, as well asprospects their development directions and trends. Through comparative analysis, it is clear that solid phase extraction(SPE) is the most commonly used pretreatment method, ultrasonic emulsion extraction (USAEME) has betterrecovery, and QuEChERS method has the characteristics of large sample enrichment and high recovery; LC, GC andMS or MS/ MS couplers are the most commonly used PPCPs detection equipment; the development of rapid, efficientand accurate analytical methods for PPCPs is a key direction for future research.