Philinopsides E and F, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis |
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Authors: | Zhang Shi-Long Li Ling Yi Yang-Hua Sun Peng |
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Affiliation: | Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, 325 Guo-He Road, Shanghai 200433, P.R. China. |
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Abstract: | Two new sulfated triterpene glycosides, philinopside E (1) and F (2), have been isolated from the sea cucumber Pentacta quadrangularis. Their structures have been established by extensive spectral analysis (NMR and MS) and chemical evidence. Glycoside 1 showed significant cytotoxicity (Ed(50) 0.75-3.50 microg mL(-1)) against ten tumor cell lines. |
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