Copper-mediated annulative direct coupling of o-alkynylphenols with oxadiazoles: a dehydrogenative cascade construction of biheteroaryls |
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| Authors: | Hachiya Hitoshi Hirano Koji Satoh Tetsuya Miura Masahiro |
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| Affiliation: | Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan. |
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| Abstract: | A copper-mediated annulative direct coupling of o-alkynylphenols with 1,3,4-oxadiazoles proceeds smoothly even under ambient conditions to afford the corresponding biheteroaryls. The reaction system represents a new avenue for the construction of biheteroaryl molecules of interest in their biological and physical properties. |
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