| 2-烷基环戊-2-烯酮的简便合成新方法 |
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| 引用本文： | 荣国斌,陶凤岗,许临晓,丁新腾,吴钧和.2-烷基环戊-2-烯酮的简便合成新方法[J].化学学报,1983,41(10):971-973. |
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| 作者姓名： | 荣国斌 陶凤岗 许临晓 丁新腾 吴钧和 |
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| 作者单位： | 复旦大学化学系 |
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| 摘 要： | 2-位取代的环戊-2-烯酮是一类重要的有机合成中间体,它们的合成方法虽然已有不少文献报道,但大都路线较长,原料难得,条件苛刻且收率较低.本文报道一个以环戊二烯为原料,仅两步反应合成2-烷基环戊-2-烯酮的简便新方法. 以聚乙二醇(PEG)作为相转移催化剂,环戊二烯在氢氧化钾作用下与卤代烷在固-液相条件下反应,可方便地得到相应的烷基取代环戊二烯,主要为1-位和2-位烷基取代异构体的混合物.通过该方法制备烷基环戊二烯较之采用钠氨于液氨中反应的通常制备方法更可取.烷基环戊二烯进一步于甲醇中经溴代及酸性水解后,即可得到2-烷基环
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| 关 键 词： | 催化剂 环戊二烯 聚氧化乙烯 相转移催化 氢氧化钾 环戊烯酮P |
A new convenient synthesis of 2-alkylcyclopent-2-enones |
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| RONG GUOBIN,TAO FENGGANG,XU LINXIAO,DING XINTENG,WU JUNHE.A new convenient synthesis of 2-alkylcyclopent-2-enones[J].Acta Chimica Sinica,1983,41(10):971-973. |
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| Authors: | RONG GUOBIN TAO FENGGANG XU LINXIAO DING XINTENG WU JUNHE |
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| Abstract: | The titled compounds were conveniently obtained in two steps from cyclopentadiene, namely alkylation of cyclopentadiene with alkyl halides and KOH in the precence of polyothylene glycol (PEG) as phase transfer catalyst to give alkylcyclo-pentadienes which were brominated and then hydrolyzed to give 2-alkylcyclopent-2 -enones with an overall yield of 20 to 30%. |
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| Keywords: | CATALYST CYCLOPENTADIENE POLYETHYLENE OXIDE PHASE TRANSFER CATALYSIS POTASSIUM HYDROXIDE CYCLOPENTENONE P |
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