幽门螺杆菌生物被膜形成及其影响因素研究进展

幽门螺杆菌(Helicobacter pylori)是人类慢性感染最常见的病原菌之一,会引发多种消化系统和非消化系统疾病.研究表明:H.pylori能在多种表面形成生物被膜,包括宿主胃黏膜表面、腺体及非生物表面等,其耐药性、感染复发与生物被膜作用相关.本文介绍了H.pylori生物被膜形成及其结构特点,并对其影响因素进...

Progress in the study of Helicobacter pylori biofilm formation and its influencing factors

Helicobacter pylori is one of the most common pathogens of chronic human infections and is commonly responsible for a wide range of digestive and non-digestive diseases. H. pylori has been shown to form biofilms on a variety of surfaces, including host gastric mucosal surfaces, glands and abiotic surfaces. Increased drug resistance and recurrence of infection have been linked to the action of the biofilm. In this article, we introduce the formation of H. pylori biofilm and its structural characteristics. The article also reviews the factors influencing the formation of H. pylori. The article is aimed to provide a method and reference for the study of the mechanism of H. pylori biofilm, in order to serve the prevention and treatment of infection in clinical settings.