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Genesis and Mechanism of Some Cancer Types and an Overview on the Role of Diet and Nutrition in Cancer Prevention
Authors:Nurkhalida Kamal  Muna Abdulsalam Ilowefah  Ayah Rebhi Hilles  Nurul Adlina Anua  Tahani Awin  Hussah Abdullah Alshwyeh  Sahar Khamees Aldosary  Najla Gooda Sahib Jambocus  Areej A. Alosaimi  Azizur Rahman  Syed Mahmood  Ahmed Mediani
Abstract:Cancer is a major disease with a high mortality rate worldwide. In many countries, cancer is considered to be the second most common cause of death after cardiovascular disease. The clinical management of cancer continues to be a challenge as conventional treatments, such as chemotherapy and radiation therapy, have limitations due to their toxicity profiles. Unhealthy lifestyle and poor dietary habits are the key risk factors for cancer; having a healthy diet and lifestyle may minimize the risk. Epidemiological studies have shown that a high fruit and vegetable intake in our regular diet can effectively reduce the risk of developing certain types of cancers due to the high contents of antioxidants and phytochemicals. In vitro and in vivo studies have shown that phytochemicals exert significant anticancer effects due to their free radical scavenging capacity potential. There has been extensive research on the protective effects of phytochemicals in different types of cancers. This review attempts to give an overview of the etiology of different types of cancers and assesses the role of phytonutrients in the prevention of cancers, which makes the present review distinct from the others available.
Keywords:cancer   diagnosis   diet   nutrition   phytochemicals   therapeutics
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