Phytochemical Constituents and Pharmacological Potential of Tamus communis Rhizomes |
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| Authors: | Iva Slavova Teodora Tomova Slavena Kusovska Yoana Chukova Mariana Argirova |
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| Affiliation: | Department of Chemical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, 15A Vassil Aprilov Str., 4002 Plovdiv, Bulgaria; (T.T.); (S.K.); (Y.C.); (M.A.) |
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| Abstract: | Tamus communis L. is a plant distributed in a number of geographical areas whose rhizome has been used for centuries as an anti-inflammatory and analgesic remedy. This review aims to summarize the current knowledge of the chemical composition and biological activity of the extracts or individual compounds of the rhizome. The data for the principal secondary metabolites are systematized: sterols, steroidal saponins, phenanthrenes, dihydrophenanthrenes, etc. Results of biological tests for anti-inflammatory action, cytotoxicity, anticholinesterase effect, and xanthine oxidase inhibition are presented. Some open questions about the therapeutic properties of the plant are also addressed. |
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| Keywords: | Tamus communis rhizome phenanthrenes sterols diosgenin anti-inflammatory cytotoxicity cholinesterase inhibitor xanthin oxidase inhibitor |
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