Aziridine Ring Opening as Regio- and Stereoselective Access to C-Glycosyl-Aminoethyl Sulfide Derivatives |
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| Authors: | Aleksandra Tracz,Martyna Malinowska,Stanisł aw Leś niak,Anna Zawisza |
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| Affiliation: | Department of Organic and Applied Chemistry, University of Łódź, 91-403 Łódź, Poland; (A.T.); (M.M.); (S.L.) |
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| Abstract: | A short synthetic route to stereoselective access to C-glycosyl-aminoethyl sulfide derivatives has been developed through the reaction of tributhyltin derivatives of glycals with aziridinecarboaldehyde and the regioselective ring opening of a chiral aziridine with thiophenol. The absolute configurations of the resulting diastereoisomers were determined by 1H NMR spectroscopy. |
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| Keywords: | glycals aziridine sulfides |
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