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Age-dependent plasticity in the superior temporal sulcus in deaf humans: a functional MRI study

Authors:	Email author" target="_blank">Norihiro?Sadato Email author Hiroki?Yamada Tomohisa?Okada Masaki?Yoshida Takehiro?Hasegawa Ken-Ichi?Matsuki Yoshiharu?Yonekura Harumi?Itoh

Institution:	(1) National Institute for Physiological Sciences, 38 Nishigonaka,Myodaiji, 444-8585 Okazaki, Japan;(2) JST/RISTEX, 2-5-1, Atago, Minato-ku, 105-6218 Tokyo, Japan;(3) Fukui University School of Medicine, 910-1193 Fukui, Japan;(4) Fukui University School of Education, 910-1193 Fukui, Japan;(5) Biomedical Imaging Research Center, Fukui University School of Medicine, 910-1193 Fukui, Japan

Abstract:	Background Sign-language comprehension activates the auditory cortex in deaf subjects. It is not known whether this functional plasticity in the temporal cortex is age dependent. We conducted functional magnetic-resonance imaging in six deaf signers who lost their hearing before the age of 2 years, five deaf signers who were >5 years of age at the time of hearing loss and six signers with normal hearing. The task was sentence comprehension in Japanese sign language.

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