Acylhydroperoxide oxidations of the anticancer agent hexamethylmelamine |
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Authors: | Mark E. Sanders Matthew M. Ames |
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Affiliation: | Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah, 84112. U.S.A;Department of Oncology, Mayo Clinic - Mayo Foundation, Rochester, Minnesota, 55901. U.S.A. |
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Abstract: | The clinically effective anticancer agent hexamethylmelamine undergoes an unusual acylhydroperoxide oxidative transformation to give the novel product 2,4-bis(dimethylamino)-6-[(dimethylamino)oxy]-1,3,5-triazine. |
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