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A general preparation of fluoroallylamine enzyme inhibitors incorporating a β-substituted heteroatom |
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| Authors: | Ian A. McDonald Philippe Bey |
| Affiliation: | Merrell Dow Research Institute, Strasbourg Center, 67084 Strasbourg, France |
| Abstract: | A general route to β-heteroatom substituted fluoroallylamines is described. This has led to the synthesis of new time-dependent inhibitors of monoamine oxidase, diamine oxidase and γ-aminobutyric acid transaminase. |
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