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Synthesis of the O-specific polysaccharide of Shigellaflexneri
Authors:N.K. Kochetkov  N.É. Byramova  Yu.E. Tsvetkov  L.V. Backinowsky
Affiliation:N.D.Zelinsky Institute of Organic Chemistry, Academy of Sciences of the U.S.S.R., MoscowU.S.S.R.
Abstract:A regular heteropolysaccharide built of tetrasaccharide repeating units is synthesised by means of regio- and stereospecific polycondensation of a tritylated cyanoethylidene derivative. The polysaccharide obtained is identical with the O-antigenic polysaccharides of Shigellaflexneri serotypes 3b, 3c, and variant Y. It also represents the basic chain of O-antigenic polysaccharides of all serotypes of this bacterium.
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