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The reactions of combined organocuprate-chlorotrimethylsilane reagents with conjugated carbonyl compounds |
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| Authors: | EJ Corey Neil W Boaz |
| Institution: | Department of Chemistry, Harvard University, Cambridge, MA 02138 USA |
| Abstract: | Organocuprates and chlorotrimethylsilane are compatible as separate species in THF or ether solution at ?50 to ?78°, and in combination can both accelerate and improve 1,4-addition reactions with conjugated carbonyl compounds. |
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