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Reformatsky type additions of haloacetonitriles to aldehydes mediated by metallic nickel
Authors:Shin-ichi Inaba  Reuben D Rieke
Institution:Department of Chemistry, University of Nebraska-Lincoln Lincoln, Nebraska 68588-0304, U.S.A.
Abstract:Nickel in the metallic state was found to carry out the Reformatsky type addition of haloacetonitriles to aldehydes via cyanomethylnickel halides to give β-hydroxynitriles in good yields.
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