Reformatsky type additions of haloacetonitriles to aldehydes mediated by metallic nickel |
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Authors: | Shin-ichi Inaba Reuben D Rieke |
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Institution: | Department of Chemistry, University of Nebraska-Lincoln Lincoln, Nebraska 68588-0304, U.S.A. |
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Abstract: | Nickel in the metallic state was found to carry out the Reformatsky type addition of haloacetonitriles to aldehydes via cyanomethylnickel halides to give β-hydroxynitriles in good yields. |
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