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The absolute configuration of α-hydroxyphosphonates
Authors:AbA Smaardijk  Simon Noorda  Fré van Bolhuis  Hans Wynberg
Institution:Department of Organic Chemistry, University of Groningen, Nijenborgh 16, 9747 AG Groningen, The Netherlands
Abstract:The absolute configuration and CD spectra of a series of chiral α-hydroxyphosphonates and phosphoric acids have been determinated. The hydroxyphosphonates were prepared via a quinine catalysed 1,2-addition reaction of phosphite to aldehyde.
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