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A synthesis of 2-alkyl-3-furoic acids |
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| Authors: | Marcus A Tius Selvaraj Savariar |
| Institution: | Department of Chemistry, University of Hawaii, Honolulu, Hawaii 96822, U.S.A. |
| Abstract: | An efficient synthesis of 2-alkyl-3-furoic acids has been developed. Addition of the lithium dianion of 4-oxo-2-phenylthiobutanoic acid ethylene acetal to aldehydes followed by acid-catalyzed cyclization produces furan products in high yield. |
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