Aziridine-2-phosphonic acid,the valuable synthon for synthesis of 1-amino-2-functionalized ethanephosphonic acids |
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| Authors: | Jan Zygmunt |
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| Institution: | Institute of Organic and Physical Chemistry, Technical University of Wroclaw, 50–370 WroclawPoland |
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| Abstract: | The ring-opening of aziridine-2-phosphonic acid with a series of nucleophiles was studied. This reaction was found to proceed regioselectively and to provide a good preparative method for the synthesis of phosphonic analogs of various 2-substituted 1-aminoethanecarboxylic acids. |
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