Conversion of 6-protoilludene into illudin-M and -S by omphalotusolearius

Deuterium labeled $\text{dl}$-6-protoilludene ($\text{7}$) was synthesized and fed to the illudin-producing fungus $\text{Omphalotus}$$\text{olearius}$ (ATCC 11719). The hydrocarbon ($\text{7}$) was incorporated into illudin-M ($\text{2}$) and -S ($\text{3}$).