Phosphane-free green protocol for selective nitro reduction with an iron-based catalyst |
| |
Authors: | Sharma Upendra Verma Praveen Kumar Kumar Neeraj Kumar Vishal Bala Manju Singh Bikram |
| |
Affiliation: | Natural Plant Products Division, Institute of Himalayan Bioresource Technology (Council of Scientific & Industrial Research), Palampur, Himachal Pradesh, 176 061, India. |
| |
Abstract: | Iron phthalocyanine with iron sulfate has been successfully applied for high chemo- and regioselective reduction of aromatic nitro compounds to give the corresponding amines in a green solvent system without using any toxic ligand. The catalytic systems were also compatible with a large range of other reducible functional groups, such as keto, acid, amide, ester, halogen, lactone, nitrile, N-benzyl, O-benzyl, hydroxy, and heterocycles. In the present study, dinitro compounds have been regioselectively reduced to the corresponding amines with high yield. In most of the cases the conversion and selectivity was greater than 99% as determined by GC-MS analysis. |
| |
Keywords: | chemoselectivity hydrazine iron phthalocyanines reduction regioselectivity |
本文献已被 PubMed 等数据库收录! |
|