The Baylis-Hillman approach to quinoline derivatives |
| |
Authors: | Familoni Oluwole B Klaas Phindile J Lobb Kevin A Pakade Vusumzi E Kaye Perry T |
| |
Affiliation: | Department of Chemistry, Rhodes University, Grahamstown, 6140, South Africa. |
| |
Abstract: | Baylis-Hillman reactions of 2-nitrobenzaldehydes with various activated alkenes afford adducts that undergo reductive cyclisation to quinoline derivatives. The chemo- and regioselectivity of cyclisation appears to be influenced by the choice of both the substrate and the reagent system, and competing reactions have been observed. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|