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The Synthesis of Bridged Purine Dinucleoside
摘    要:Nuc1eosides/tideswithmodificahonareofinterestinconnectionwiththeirpossiblebiologicalactivity,somemodifiedpurinederivativeshavelicensedforantiviraltheraPeuticagentSsuchasAIa-A,cyc1ardin,6-deoxyaCyclovir,acylovir,DHPHandDHBEI1].Duringrecenyears,greatattentionhasbeenfocusedonseveralderivahvesof2,6-diaminoTdrie,andsomederivativeshaveshowedanhviralachvityagainstHIVl231.lnthispaPer,wewishtorePortthesynthesisofthebridgedpurinedinudeosidesinfollowingroute(schemel).Thesynthesis0ftargetc0mPounds…

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