| 手性双季铵盐诱导下的硝基甲烷与查尔酮的Michael反应 |
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| 引用本文： | 陈继俊,杜争鸣,施耀曾,朱文胜,胡宏纹.手性双季铵盐诱导下的硝基甲烷与查尔酮的Michael反应[J].有机化学,1992(6). |
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| 作者姓名： | 陈继俊 杜争鸣 施耀曾 朱文胜 胡宏纹 |
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| 作者单位： | 南京大学化学系，南京大学化学系，南京大学化学系，南京大学化学系，南京大学化学系 南京，210008，南京，210008，南京，210008，南京，210008，南京，210008 |
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| 摘 要： | 双季铵盐相转移催化剂具有用量少、催化活性高的特点,比单官能团相转移催化剂的催化性能更为显著。手性季铵盐是进行不对称
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| 关 键 词： | 不对称诱导 双季铵盐 Michael加成 |
Chiral Bis-quaternary Ammonium Salts Induction Michael Addition of Nitromethane and Chalcone |
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| CHEN Ji-Jun,DU Zhen-Ming,SHI Yao-Zeng,ZHU Wen-Sheng,HU Hong-Wen.Chiral Bis-quaternary Ammonium Salts Induction Michael Addition of Nitromethane and Chalcone[J].Chinese Journal of Organic Chemistry,1992(6). |
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| Authors: | CHEN Ji-Jun DU Zhen-Ming SHI Yao-Zeng ZHU Wen-Sheng HU Hong-Wen |
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| Institution: | CHEN Ji-Jun,DU Zhen-Ming,SHI Yao-Zeng,ZHU Wen-Sheng,HU Hong-Wen Department of Chemistry,Nanjing University,210008 Nanjing |
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| Abstract: | The chiral bis-quaternary ammonium salts, 1,8-bis (1S,2R)-N-(2-hydroxy-1-
methyl-2-phenyl) et y1-N, N-dimethylammonium]-3, 6-dioxaoctane diiodide (BDMEO I) and
1,11-bis (1S,2R)-N-(2-hydroxy-1-methyl-2-phenyl) ethyl-N, N-dimethylammonium]-3,
6,9-trioxaundecane diiodide (BDMEU I), were synthesized and their selectivity was stu-
died in Michael addition of nitromethane and chalcone. The enantiomeric excess was 27.0%
The effect of solvents on the stereoselectivity was also discussed. |
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| Keywords: | asymmetric induction bis-quaternary ammonium salt Michael addition |
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