A Sequence of Aldol Condensations and a Michael Addition Giving a Cyclohexenone Ring System |
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| Authors: | Ulrich Kuhl and Ulrike Holzgrabe |
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| Institution: | (1) National Research Council of Italy, Institute of Biomolecular Chemistry, Via Paolo Gaifami 18, 95126 Catania, Italy; |
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| Abstract: | The reaction of 1,5-diphenylpentanetrione, 4-chlorobenzaldehyde, and acetone in the presence of methylamine resulted in 2,6-dibenzoyl-5-(4-chlorphenyl)-3-methyl-cyclohex-2-en-1-one, which was formed by a sequence of a Knoevenagel reaction, an aldol condensation, and a Michael addition in a one-pot reaction. |
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