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Two new lignans from Dipteronia dyeriana
Authors:Rong Guo  Min Luo  Chun Lin Long  Ma Lin Li  Zhi Qin Ouyang  Yi Ping Zhou  Yue Hu Wang  Xing Yu Li  Ya Na Shi
Institution:a Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;Yunnan Agricultural University, Kunming 650201, China;b Yunnan Agricultural University, Kunming 650201, China;c Yunnan Laboratory of Pharmacology for Natural Products, Kunming Medical College, Kunming 650031, China;d Yunnan Introduction & Propagation Center for Rare & Endangered Plants, Kunming 650032, China
Abstract:A new sesquilignan,7',8'-didehydroherpetotriol(1),and a new lignan glycoside,( )-isolariciresinol-9'-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(2),were isolated from the branches of Dipteronia dyeriana.Their structures were elucidated by spectroscopic methods and chemical evidence.Compound 1 possessed inhibitory activity against human leukaemia K562 cells with an IC50 value of 39 μmol/L.
Keywords:raceae  Dipteronia yeriana  Lignans  Didehydroherpetotriol  Leukaemia
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