New pi-extended water-soluble squaraines as singlet oxygen generators |
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| Authors: | Beverina Luca Abbotto Alessandro Landenna Mirko Cerminara Michele Tubino Riccardo Meinardi Francesco Bradamante Silvia Pagani Giorgio A |
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| Affiliation: | Department of Materials Science and INSTM, University of Milano-Bicocca, Via Cozzi 53, I-20125 Milano, Italy. |
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| Abstract: | [graph: see text] Condensation of squaric acid with a number of differently substituted 2-pyrrolyl derivatives afforded three new classes of squaraines. Their sharp and intense absorption bands in the biological window (700-900 nm), inherent singlet oxygen generation capabilities, together with proper functionalization allowing good water solubility make them suitable candidates as new non-porphyrinic singlet oxygen photosensitizers for photodynamic therapy (PDT). |
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