| Affiliation: | Danni Chen 1,2,Gaixia Xu 2,Bahi Ahmed Ali 3,4,Ken-Tye Yong 5,Cuihong Zhou 3,Xiaomei Wang 3,Junle Qu 2,Paras N. Prasad 6,and Hanben Niu 2 1 College of Optoelectronic Science and Engineering,Huazhong University of Science and Technology,Wuhan 430074,China 2 Institute of Optoelectronics,Key Lab of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province,Shenzhen Key Lab of Biomedicine Engineering,Shenzhen University,Shenzhen 518060,China 3 College of Medicine,... |
| Abstract: | We study the uptake and distribution of transferrin (Tf)-conjugated CdSe/CdS/ZnS quantum dots (QDs) in single living HeLa cells with both fluorescence confocal microscopy and three-dimensional (3D) reconstruction technique. By increasing the co-incubation time or the dosage of QDs-Tf, we find that the uptake of QDs-Tf bioconjugates in the cells increases correspondingly, but with different uptake rates. Additionally, the distribution of QDs-Tf, in single live HeLa cells is time dependent. To our knowledge, ... |
