Nitration‐Oximization of Styrene Derivatives with tert‐Butyl Nitrite: Synthesis of α‐Nitrooximes |
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| Authors: | Napasawan Chumnanvej Praewpan Katrun Manat Pohmakotr Vichai Reutrakul Darunee Soorukram Chutima Kuhakarn |
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| Affiliation: | Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH‐CIC), Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand |
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| Abstract: | A highly efficient method for direct nitration‐oximization of styrene derivatives using tert‐butyl nitrite (t‐BuONO) in DMSO was developed. The present method offers a convenient and practical approach for the synthesis of α‐nitrooximes in moderate to high yields. The salient features entail mild reaction conditions, metal‐free reagent, environmentally benign solvent and simple experimental procedure. |
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| Keywords: | α ‐nitrooximes tert‐butyl nitrite nitration‐oximization styrenes |
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