Rhodium(III)/Amine Synergistically Catalyzed Enantioselective Alkylation of Aldehydes with α,β‐Unsaturated 2‐Acyl Imidazoles |
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| Authors: | Jun Gong Kuan Li Saira Qurban Qiang Kang |
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| Affiliation: | 1. Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China;2. Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China |
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| Abstract: | A synergistic catalysis combination of chiral‐at‐metal rhodium complex and amine catalyst was developed for enantioselective alkylation of aldehydes with α,β‐unsaturated 2‐acyl imidazoles. The corresponding adducts were obtained in good yields with excellent enantioselectivities (up to 99% ee). |
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| Keywords: | alkylation of aldehyde chiral‐at‐metal complex synergistic catalysis |
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