| 恩曲他滨的波谱学数据与结构确证 |
| |
| 引用本文： | 陈仕云,何勇,余三喜,高永好,江浩,吴宗好. 恩曲他滨的波谱学数据与结构确证[J]. 波谱学杂志, 2013, 30(3): 398-405 |
| |
| 作者姓名： | 陈仕云 何勇 余三喜 高永好 江浩 吴宗好 |
| |
| 作者单位： | 合肥学院化学与材料工程系,安徽合肥,230601;合肥华方医药科技有限公司,安徽合肥,230088 |
| |
| 摘 要： | 对恩曲他滨化合物1的紫外吸收光谱(UV)、红外吸收光谱(IR)、核磁共振氢谱(1H NMR)、氢-氢相关谱(1H-1H COSY)、核磁共振碳谱13C NMR、DEPT谱、碳氢相关谱(HMQC)、碳氢远程相关谱(HMBC)及质谱(MS)进行了解析，对其所有的NMR谱信号进行了归属，纠正了文献[11]中的归属错误，讨论了红外光谱特征吸收峰所对应的官能团的振动形式，通过上述多种波谱技术确证了恩曲他滨的结构.
|
| 关 键 词： | 核磁共振(NMR) 归属 恩曲他滨 结构确证 |
| 收稿时间： | 2012-12-08 |
Spectral Analysis and Structural Elucidation of Emtricitabine |
| |
| CHEN Shi-yun , HE Yong , YU San-xi , GAO Yong-hao , JIANG Hao , WU Zong-hao. Spectral Analysis and Structural Elucidation of Emtricitabine[J]. Chinese Journal of Magnetic Resonance, 2013, 30(3): 398-405 |
| |
| Authors: | CHEN Shi-yun HE Yong YU San-xi GAO Yong-hao JIANG Hao WU Zong-hao |
| |
| Affiliation: | 1. Department of Chemical and Materials Engineering, Hefei University, Hefei 230601，China; ;2. Hefei Huafang Pharmaceutical Science & Technology Co., Ltd., Hefei 230088, China |
| |
| Abstract: | The spectral data of Emtricitabine were reported, including UV, IR, NMR (1H NMR, 1H-1H COSY, 13C NMR, DEPT, HMQC and HMBC) and MS data. The NMR signals were assigned. The infrared spectrum was analyzed to derive the types of vibrations of the functional groups in this compound. The molecular structure of emtricitabine was determined. |
| |
| Keywords: | NMR assignment Emtricitabine structural identification |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《波谱学杂志》浏览原始摘要信息 |
|
点击此处可从《波谱学杂志》下载全文 |
|
