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Synthesis and configuration of 4-alkyl-2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide
Authors:Evelyne Grander,G  rard Leclerc,Jean-Daniel Ehrhardt
Affiliation:Evelyne Grander,Gérard Leclerc,Jean-Daniel Ehrhardt
Abstract:4-Alkyl-2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide 5, 6 and 7 were obtained from 2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide 1 by reaction of its anion 4 with alkyl halides. cis- and trans-Configuration of the 4-alkylated products were determined by 1H-nmr and NOE difference spectro-scopy studies.
Keywords:
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